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ADAMTS-5 Inhibitor

CAS No. 929634-33-3

ADAMTS-5 Inhibitor ( —— )

Catalog No. M26598 CAS No. 929634-33-3

ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 μM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 133 Get Quote
10MG 195 Get Quote
25MG 323 Get Quote
50MG 480 Get Quote
100MG 692 Get Quote
500MG 1422 Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    ADAMTS-5 Inhibitor
  • Note
    Research use only, not for human use.
  • Brief Description
    ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 μM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).
  • Description
    ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 μM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    5-HT2A; D1 receptor; D5 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    929634-33-3
  • Formula Weight
    449.9
  • Molecular Formula
    C16H11ClF3N3OS3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cn1nc(c(\C=C2/SC(=S)NC2=O)c1SCc1ccc(Cl)cc1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.1. Rostom SA. Novel fused pyrrole heterocyclic ring systems as structure analogs of LE 300: Synthesis and pharmacological evaluation as serotonin 5-HT(2A), dopamine and histamine H(1) receptor ligands. Arch Pharm (Weinheim). 2010 Feb;343(2):73-80.
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